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Association between uric acid levels and graft-versus-host disease

Study number:
Type of transplant:
Short title:
Uric Acid Study
Study status:
Recruiting / Data Collection
Deadline for data collection:
Study design:
Prospective study
Primary objective:
To assess if uric acid acting as danger signal and released during conditioning therapy is associated with occurence and severity of acute GvHD​
Key inclusion criteria:
First allo-SCT from HLA-matched sibling donors given stem cell grafts (bone marrow or peripheral blood) without T cell depletion, patients with AL, MDS or Lymphoma, Myeloablative and dose-reduced conditioning
Principal investigator:
Olaf Penack
Principal investigator email:
EBMT Study coordinator:
Steffie van der Werf