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JACIE Activity Report 2021

Standards and Accreditation – JACIE

JACIE logo

The Joint Accreditation Committee ISCT-Europe & EBMT (JACIE) was established in 1998. It promotes high-quality patient care and laboratory performance in the collection, processing and administration of cellular therapy through a profession-led, voluntary accreditation scheme.

JACIE works continuously with international partner organisations to develop and maintain standards for the provision of quality medical and laboratory practice in HSCT, performs on-site inspections, and accredits those programmes that demonstrate compliance with these standards. JACIE also provides training for inspectors and centres on the accreditation process.

Since 2000, 508 transplant programmes and facilities in 34 countries in Europe and beyond have applied to JACIE and 790 inspections (first-time and reaccreditation) have been performed. 368 applicants have achieved accreditation at least once with practically all centres repeating the process after the first accreditation cycle. There are over 300 registered inspectors, all volunteers drawn from the HSCT and cellular therapy field.

In terms of activity, 2021 continued to see severe negative impact of the pandemic on activities although this has been somewhat mitigated by the introduction of a remote inspection format and a so-called Short Process which avoid the need for inspectors to travel. 70 applications were received, 31 inspections of different formats were performed and 28 accreditations were awarded.


JACIE Applications
Figure 1 Number of applications received per year


JACIE Inspections
Figure 2 Number of inspections performed per year.


JACIE Activity Report 2020_Accreditations
Figure 3 Number of accreditations awarded per year


The second benchmarking exercise was performed in July 2021. A total of 395 centres were eligible to participate in the 2021 exercise. Of the notified centres, 68% (260 centres) were able to pick up the report: 200 directly through Google Drive access, 36 through their national registries and 24 were sent directly to the centres that were not able to access the drive themselves.

The majority (95%) of the centres that evaluated the report found the content comprehensible. 98% evaluated the quality as good and considered the current report an improvement on the previous release/version.

8th Edition of FACT-JACIE Standards

The 8th edition of the FACT-JACIE Standards was published in May 2021.



The JACIE Twitter account @JACIE_EBMT has grown to 1,789 followers.

We would like to express our continued appreciation and admiration for the Inspectors, JACIE Committee Members, Accreditation, Standards and Quality Manager Committee members, other volunteers and the JACIE Office team for all their tremendous hard work, commitment and dedication.

Institutions awarded accreditation in 2021

  1. Hospital Privado Universitario de Córdoba, Córdoba, Argentina
  2. Institut Jules Bordet, Brussels, Belgium
  3. CHU Haut-Levêque, Pessac (Bordeaux), France
  4. Bayerische Stammzellbank gGmbH, Gauting, Germany
  5. Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel
  6. Istituto L.e A. Seràgnoli, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
  7. Ospedale Civile di Civitanova Marche Area Vasta 3 Marche, Civitanova Marche, Italy
  8. Ospedale Policlinico San Martino, Genova, Italy
  9. Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
  10. Azienda Unità Sanitaria Locale IRCCS Reggio Emilia, Reggio Emilia, Italy
  11. Rome Transplant Network, Policlinico Tor Vergata, Rome, Italy
  12. Humanitas Cancer Center, Rozzano, Italy
  13. AOU Integrata Verona, Verona, Italy
  14. King Faisal Specialist Hospital, Riyadh, Saudi Arabia
  15. Hospital Universitario de la Paz, Madrid, Spain
  16. Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain
  17. Hospital Universitario y Politécnico de La Fe, Valencia, Spain
  18. University Hospital, Linköping, Sweden
  19. Kantonsspital Aarau AG, Aarau, Switzerland
  20. Universitätsspital Basel, Basel, Switzerland
  21. Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland
  22. Universitätspital Zürich, Zürich, Switzerland
  23. NHS Blood and Transplant, Barnsley, United Kingdom
  24. University Hospital of Wales, Cardiff and Vale University Health Board and Singleton Hospital, Abertawe Bro Morgannwg University Health Board, Cardiff/Swansea, United Kingdom
  25. Leeds Teaching Hospitals NHS Trust, Mid Yorkshire NHS Trust, NHS Blood and Transplant Leeds, Leeds, United Kingdom
  26. Alder Hey NHS Foundation Trust, Liverpool, United Kingdom
  27. NHS Blood and Transplant, Liverpool, United Kingdom
  28. Biovault Technical Ltd, Plymouth, United Kingdom

Full list available at


Dr. Kim Orchard (Southampton, UK) succeeded Prof. John Snowden as Chair of the JACIE Committee in mid-2020. Prof. Snowden, now the EBMT Secretary, remains on the Committee. See for more details.

Dr. Isabel Sánchez Ortega joined EBMT in March 2020 as Medical Officer. Among her responsibilities is supporting JACIE. Dr. Sánchez Ortega took over the JACIE Medical Director duties from Dr. Riccardo Saccardi, who occupied this role from January 2016 to June 2020.

Quality Managers Committee

The Quality Managers Committee was established in 2011. All of the members are experienced quality managers or responsible for quality management working in accredited centres or towards accreditation. The Committee is chaired by Ms. Renza Monteleone (Reggio Calabria, IT). See for more details.

JACIE Accreditation Committee - Activity Report 2021

2021 saw a significant downturn in the activity of the JACIE Accreditation Committee from its previous activity level of 2 teleconferences per month, commensurate with the cessation of on-site inspections of stem cell transplant programmes as a result of the COVID pandemic.

Four teleconferences were undertaken:

18/01/2021 - Pavia, Italy - On-site
16/08/2021 - 
Manchester, UK - Pilot: remote
Rome, Italy    Pilot: remote
20/09/2021 - Creteil, France- Pilot: remote

Centre Inspection Round Areas Inspected
Pavia, Italy Reaccreditation 1 Clinical paediatric, BM paediatric and apheresis collection (due inspection in2022: clinical adult+IEC, BM adults collection, processing).
Manchester, UK Reaccreditation 2 Processing
Rome, Italy Reaccreditation1 Clinical paediatric (auto/allo) + IEC, BM and apheresis collection
Creteil, France Reaccreditation 2 Clinical adult (allo)+IEC, BM and apheresis collection, processing

Reports from the three pilot inspections using the new remote inspection process were reviewed at the two teleconferences in August / September.

A further teleconference is scheduled for mid-December dependent upon availability of the inspection report which will be the first desk-top documentation review of a Centre assessed to be low risk (and so eligible for documentation review only) as per the Short (inspection) Process.

See for more details.

JACIE Inspector Committee – Activity Report 2021

The JACIE Inspector Committee (JIC) is the newest of the JACIE sub-committees founded in September 2020 meeting monthly during its first year. The committee members represent inspectors for all areas of JACIE standards and the key objectives of the committee are

  • Contribute to the development of the inspection format
  • Making recommendations for retention strategies
  • Making recommendations for development of continuing training and education

During its first year, JIC has focussed on two key areas:

Firstly, JIC has worked with JACIE office on developing different models for the JACIE Inspections as the Covid pandemic has exposed the fragility of the existing inspection model. Pilot project for full remote inspection pilots took place in June- July 2021 and has now been rolled out as an alternative to full onsite inspection. Further, JIC developed a checklist for Short Process – inspections, to add an additional option for centres whose inspections where delayed due to the first wave of the pandemic.

Secondly, the Committee also increased the engagement with the wider inspector community. The bi-monthly virtual Inspector Sessions commenced in June 2021. This forum aims to update the inspectors in changes within JACIE as well as provide a forum for feedback from the wider inspector community. The first sessions have focussed on training on the new processes and the 8th edition of JACIE standards with sessions on reporting and role of the team leader planned going forward. All the sessions are now available on EBMT e-learning platform. JIC is also using the relaunched inspectors’ LinkedIn group to disseminate information.

The future plans for 2022 include development of virtual inspector training modules.

See for more details.