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Trends in donor characteristics for unrelated Stem Cell Transplantation in patients with acute myeloid leukemia

Acute Leukemia Working Party (ALWP)
Study type:
Study number:
Type of Stem Cell Treatment:
Acute Myeloid Leukaemia (AML)
Short title:
Trends in donor characteristics for unrelated SCT in AML
Primary objective:
To assess :
1. trends in donor characteristics in unrelated stem cell transplantation from 9-10/10 HLA compatible donors in patients with acute leukemia both AML and ALL and
2. assess their impact on transplantation outcome. We will look on three decades and compare putative between the most recent transplantation decade 2019-2019 to the 2 previous ones
Key inclusion criteria:
• De novo AML and ALL
• All disease status
• adults, age ≥ 18 years
• 9-10/10 HLA compatible unrelated donor transplants
• Transplant dates 1989- 2019
• PBSC or bone-marrow as the stem cell source
• Myeloablative or Reduced- intensity conditioning
Principal investigator:
Arnon Nagler