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The impact of pre-transplant extramedullary disease on the outcome of allogeneic hematopoietic cell transplantation for Acute Myeloid Leukemia in Children- A combined CIBMTR and EBMT analysis

Paediatric Diseases Working Party (PDWP)
Study number:
8417024
Short title:
 
Study status:
Fusion of the database EBMT CIBMTR
Deadline for data collection:
 
Study design:
 
Primary objective:
To describe the clinical characteristics and outcomes (OS, DFS, NRM, relapse incidence) of pediatric patients with AML presenting with EMD and identify prognostic factors associated with improved outcome.
Key inclusion criteria:
All patients ≤18 years of age who are affected by extramedullary disease associated with AML any time prior to transplantation with or without bone marrow involvement and who underwent an allo-HCT between 2008 and 2017.
Country:
 
Principal investigator:
Kanchan Rao
Principal investigator email:
 
EBMT Study coordinator:
Arnaud Dalissier