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Incidence and outcome of CMV and EBV reactivations after autologous HSCT for autoimmune diseases: a retrospective survey from the Autoimmune Diseases Working Party (ADWP) of the European Society for Blood and Marrow Transplantation (EBMT)

Autoimmune Diseases Working Party (ADWP)
Study type:
Study number:
Type of Stem Cell Treatment:
Auto immune disorders
Short title:
CMV EBV reactivation
Primary objective:
To identify the cumulative incidence, risk factors and outcome of CMV/EBV viraemia (ie, virus detection without clinical symptoms), CMV/EBV disease (ie, detection of viraemia and clinically relevant end organ disease) and CMV/EBV clinically significant infection (CMV/EBV viraemia leading to pre-emptive treatment) in patients who received autologous HSCT for an autoimmune disease (AD) at 100 days and 1 year following auto-HSCT. To assess centre practice in screening and treatment of CMV and EBV in the context of auto-HSCT for AD.
Key inclusion criteria:
All patients registered in the EBMT database receiving a first autologous HSCT for AD between 2009 and 2019
Principal investigator:
Tobias Alexander
EBMT Study coordinator:
Manuela Badoglio
Study coordinator email: