Top Back to top

Comparison of Cyclophosphamide/ATG vs BEAM/ATG conditioning regimens in autologous HSCT for Multiple Sclerosis

Autoimmune Diseases Working Party (ADWP)
Study number:
8410026
Short title:
BEAMCYC
Study status:
Closed
Deadline for data collection:
 
Study design:
Observational retrospective multicentre
Primary objective:
Provide data about safety and efficacy of HD-Cyclophosphamide/ATG vs BEAM/ATG conditioning regimens in severe Multiple Sclerosis
Key inclusion criteria:
• Diagnosis of MS according to the 2010 revised McDonald’s criteria
• Availability of a detailed MS clinical history, including disability progression and relapse rate in the 2 years before the HSCT
• Availability of information about previous DMAs administered
• Patients aged 18 or more at time of transplant
• First aHSCT
• Availability of a clinical follow-up, including regular neurological assessment and MRI scans.
Country:
 
Principal investigator:
Riccardo Saccardi
Principal investigator email:
 
EBMT Study coordinator:
Manuela Badoglio
Study coordinator email:
manuela.badoglio@upmc.fr