The EBMT Nurses Group kindly invites you to participate in our survey on Variation in hydration use after reinfusion of autologous stem cells in dimethyl sulfoxide (DMSO).
In Europe, autologous hematopoietic stem cell transplantation (auto-HSCT) has recently regained interest and is the standard of care for some disease states of acute myeloid leukemia (AML) and in the early phases of certain lymphoid malignancies. Upon mobilization, the patient’s HSCs are collected and cryopreserved. The most commonly used cryoprotectant is DMSO. Adverse events can occur during or after infusion of cryopreserved HSCs containing DMSO.
Hydration is known to be applied after auto-HSCT to reduce toxicity of DMSO. However, literature on this treatment is scarce and available reports show contradictory results. This survey aims to clarify the need for hydration by describing current hydration practices after auto-HSCT of EBMT member centers and exploring the reasons behind hydration after auto-HSCT. The results will aid to inform clinical guidelines on hydration after auto-HSCT.
We would be very grateful if you would offer your support and share your centre’s experience by filling in our survey.
The questionnaire will require about 15-20 minutes to complete. It is possible to complete the survey in multiple sessions, but only if you use the same computer (i.e. IP address) doing so.
Your support is greatly appreciated!
Jantina Kortleve – Principal Investigator
Maaike Söhne – Study Investigator
Brian Piepenbroek – Data Manager of the EBMT Nurses Group
Sarah Liptrott – Chair of the Nurses Group Research Committee