The following list represents Studies for which calls for participation are currently open. Learn about the individual studies below, and click the link to find out more about the Working Party responsible for the study.
While, until recently, Non-Tuberculous Mycobacteria (NTM) were considered to be rarely involved in post-transplant complications, they are now rapidly emerging pathogens in the hematopoietic stem cell transplant (HSCT) population. Since NTM infections have received little attention so far, data on the incidence and prevalence of these infections is scarce.
Therefore, this case-control study aims to investigate the clinical, radiological and microbiological characteristics of NTM infections in HSCT patients, and also identify risk factors for these infections.
We ask you to include two controls for each case. For the cases, we would like to include patients, irrespective of type of transplant (autologous or allogeneic), age, underlying disease or year of transplant, who meet the following inclusion criteria:
- History of allogeneic and/or autologous HSCT
- Diagnosis of NTM infection between 01/01/2005 and 30/09/2022
- Clinical sample yielding NTM after HSCT (i.e. from the start of conditioning)
- Suggestive clinical and/or radiological signs of NTM infection
For the controls, we would like to include patients who meet the following inclusion criteria:
- Never had a NTM infection
- The same type of transplant as the case (allogeneic or autologous)
- The same age category as the case (being a child (< 18 years old) or an adult (≥ 18 years old))
- Survived after transplant for at least as long as the case until the case developed the NTM infection