Welcome to our EBMT Nurses' Practical Skills site, where you will find three expert-led educational videos developed by the EBMT Nurses Group to support safe, high-quality, patient-centred care in clinical practice. These resources provide clear, step-by-step guidance on key procedures in haematology, stem cell transplantation and cellular therapy, including how to perform bone marrow aspiration and trephine biopsy, how to safely insert and manage a peripherally inserted central catheter (PICC), and how to thaw and infuse cryopreserved stem cells and CAR T-cells, helping nurses and allied healthcare professionals strengthen competency, confidence and consistency in patient care.
Primary collaborators:
Michelle Kenyon, Department of Haematology, King’s College Hospital NHS Foundation Trust, London, United Kingdom
Hilda Mekelenkamp, Willem-Alexander Children’s Hospital, Department of Paediatrics, Leiden University Medical Center, The Netherlands
John Murray, Haematology and Transplant Unit, The Christie NHS Foundation Trust, Manchester, United Kingdom
Acknowledgements:
Daphna Hutt, Department of Paediatric Haematology-Oncology and BMT, Edmond and Lily Safra Children’s Hospital, Sheba Medical Centre, Ramat Gan, Israel
Videos
How to Bone marrow Aspirate and Trephine
This expert-led EBMT Nurses Group video was developed jointly by The Christie School of Oncology. It provides a comprehensive, practical guide to performing bone marrow aspiration and trephine biopsy safely and confidently in clinical practice. Presented by an experienced Advanced Nurse Practitioner, John Murray, it covers indications, consent, patient preparation, pain management, equipment, technique, sample handling and post-procedure care. Ideal for nurses and clinicians involved in haematology and stem cell transplantation, the video supports high standards of training, competency and patient-centred care in outpatient bone marrow procedures.
This video was developed jointly by The Christie School of Oncology and The European Bone Marrow Transplantation Society.
Acknowledgements:
Claire Horgan, Paediatric Bone Marrow Transplant, Royal Manchester Children's Hospital, Manchester NHS Foundation Trust, Manchester, UK
Nico Gagelmann, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
How to Insert and Manage a Peripherally Inserted Central Catheter (PICC)
This educational video by the EBMT Nurses Group provides a clear overview of the safe insertion, management and care of peripherally inserted central catheters (PICCs) for nurses, allied healthcare professionals, and patients and their families involved in haematopoietic stem cell transplantation and cellular therapy. It explains the indications for PICC use, pre-procedure patient assessment and contraindications, and outlines the sterile insertion technique using real-time ultrasound guidance, including tip confirmation and catheter fixation. The video also covers catheter maintenance, flushing protocols, recognition and management of potential complications such as infection, occlusion and thrombosis, appropriate catheter selection, and safe blood sampling. Finally, it emphasises patient and caregiver education prior to discharge to ensure ongoing PICC care and prompt identification of problems.
Acknowledgements:
Ton Van Boxtel, past EBMT Nurses Group President (1991-1993), co-founder in 2009 of WoCoVA (World Congress Vascular Access)
How to Thaw and Infuse Cryopreserved Stem Cells and CAR T-Cells
This professionally produced EBMT Nurses Group video offers a practical, step-by-step guide to the safe thawing and infusion of cryopreserved haematopoietic stem cells and CAR T-cell therapy. Designed for nurses and allied healthcare professionals working in haematopoietic stem cell transplantation and cellular therapy—and suitable for sharing with patients and families—it highlights best practice, patient safety and clinical preparedness throughout the procedure. Combining clear explanations with clinical insight, the video supports high-quality care, confidence in practice and consistent standards across transplant and cellular therapy services.
Literatures
The European Blood and Marrow Transplantation Textbook for Nurses. Kenyon M, Babic A, editors
See:
Chapter 4. Transplant Preparation
Caroline Bompoint, Alberto Castagna, Daphna Hutt, Angela Leather, Merja Stenvall, Teija Schröder, Eugenia Trigoso Arjona, and Ton Van Boxtel
4.7 Transplant Workup
4.8 Venous Access Devices: Principles of Placement and Care
Chapter 6. Principles of Conditioning Therapy and Cell Infusion
Sara Zulu and Michelle Kenyon
6.6 Cell Infusion