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Retrospective study on the incidence and outcome of Adenovirus infections in patients who undergo haploidentical SCT

Infectious Diseases Working Party (IDWP)
Type d'étude:
Numéro de l'étude:
84140140
Type de traitement à base de cellules souches:
Allogeneic - Haploidentical
Maladies:
 
Titre court:
ADV infections in hapoidentical transplanted patients
Objectif principal:
1. To retrospectively evaluate the incidence of Adenovirus infection in patients transplanted with haploidentical SC either T cell ex-vivo depleted (manipulated, alfa/beta/CD19 or CD45RA depleted or other) or or with cyclophosphamide post-HSCT in centers that perform routine surveillance (2 times per week, 1 time per week, every 2 weeks) for adenovirus or research adenovirus according to patient’s symptoms or immune recovery
2. To compare the incidence of "clinically significant infection", "proven/probable disease" and "mortality adenovirus-related" in these different haploidentical transplant platforms
Principaux critères d'inclusion:
- transplant received from 01/01/2015 to 31/12/2020 with an expected end of follow-up on 31/06/ 2021
- Adenovirus infection that occurred within 180 days following HSCT
Pays:
 
Investigateur principal:
Maura Faraci
Coordinateur EBMT de l'étude:
Lotus Wendel
E-mail du coordinateur de l'étude:
idwp.ebmt@lumc.nl