Inborn Errors Working Party (IEWP)
Study type:
Study number:
8427017
Type of Stem Cell Treatment:
Allogeneic - Haploidentical
Diseases:
Other non-malignant disorders
Short title:
TCR αβ or PTCY mismatched HSCT in PID
Primary objective:
To compare overall and event free survival between the two groups. Events defined as graft failure, disease recurrence, severe chronic GVHD and severe autoimmunity or death
Key inclusion criteria:
Diagnosis: Primary Immunodeficiency/Autoimmune/Autoinflammatory disorders
Type of HSCT: first HSCT with either CD3+TCR αβ/CD19 depletion in vitro or with post-transplant cyclophosphamide in vivo
Donors: mismatched donors, either haploidentical MMFD or ≤9/10 MMUD, BM and PBSC
Date of first date of HSCT: 1.1.2010-31.12.2018
If you wish to participate in this study and did not receive an invitation please contact: iewpebmt@lumc.nl
Type of HSCT: first HSCT with either CD3+TCR αβ/CD19 depletion in vitro or with post-transplant cyclophosphamide in vivo
Donors: mismatched donors, either haploidentical MMFD or ≤9/10 MMUD, BM and PBSC
Date of first date of HSCT: 1.1.2010-31.12.2018
If you wish to participate in this study and did not receive an invitation please contact: iewpebmt@lumc.nl
Country:
Principal investigator:
Mary Slatter & Michael Albert
EBMT Study coordinator:
Sheree Hazelaar
Study coordinator email:
iewpebmt@lumc.nl