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This page features regularly updated information on EBMT sponsored and collaborative studies.

Filter your search by the trial name, a keyword or by Working Party. Set the pull-down menu to '[All]' to widen your search.

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Trial
Keyword
Working Party
Click on the Study Code to access full details of the study
Study Code ADA-SCID
Study Title Transfer of the ADA gene in hematopoietic stem/progenitor cells and peripheral blood lymphocytes for the treatment of patients affected by SCID due to ADA deficiency
Keywords ADA, SCID, gene therapy

Study Code Allo-MDS2x2
Study Title
A Prospective 2x2 Randomized Study Evaluating the Role of Remission Induction and Consolidation Chemotherapy Prior to Allogeneic Stem Cell Transplantation and Mobilised Peripheral Blood Stem Cells versus Bone Marrow Stem Cells using HLA-identical Ssiblings in Patients Less than 50 Years of Age with Myelodysplastic Syndromes and 5% to 20% Bone Marrow Blasts
Keywords MDS, myelodysplasia, 2x2, allogeneic, HLA-identical, consolidation chemotherapy, remission

Study Code AlloRIC-MMM
Study Title
Allogeneic Stem Cell Transplantation after Dose-Reduced Intensity Conditioning Regimen for Patients with Myelofibrosis with Myeloid Metaplasia
Keywords myelofibrosis, myeloid metaplasia, RIC, allogeneic

Study Code ASTIC
Study Title
Autologous Stem Cell Transplantation for Crohn’s Disease: Autologous Stem Cell Transplantation International Crohn’s Disease Trial
Keywords crohn's, autologous, ASTIC

Study Code ASTIMS
Study Title
High Dose Immunoablation and Autologous Stem Cell Transplantation versus Mitoxantrone Therapy in Severe Multiple Sclerosis
Keywords high dose, autologous, mitoxantrone, severe, multiple sclerosis, MS, ASTIMS

Study Code ASTIS
Study Title
High dose immunoablation and autologous hematopoietic stem cell transplantation versus monthly intravenous pulse therapy
Autologous Stem cell Transplantation International Scleroderma ('ASTIS') Trial
Keywords high dose, immunoablation, autologous, pulse therapy, scleroderma, sclerosis, ASTIS

Study Code CLL3R / MRC CLL5
Study Title
The Value of Autografting Younger Patients with High-risk Chronic Lymphocytic Leukemia (CLL). A Randomized phase III Intergroup Trial
Keywords CLL, chronic lymphocytic, autologous, autograft

Study Code HD-R Allo
Study Title
Allogeneic peripheral blood progenitor cell transplantation after reduced conditioning for primary refractory or relapsed Hodgkin's Disease
Keywords hodgkin's, allogeneic, RIC, primary refractory, relapse

Study Code HIDOC-EIS
Study Title
A Randomised Phase III Trial of Sequential High Dose Chemotherapy or Standard Dose Chemotherapy for Optimally Debulked FIGO Stage III and IV Ovarian Cancer
Keywords high dose, ovarian, HIDOC, OVCAT

Study Code IDWP-01
Study Title
Comparison between early and late immunization with three doses of an heptavalent pneumococcal conjugate vaccine in allogeneic stem cell transplant recipients
Keywords immunization, vaccine, allogeneic, prevenar, IDWP

Study Code LYM-1
Study Title
Randomised Study of Rituximab (MabThera) in Patients with Relapsed or Resistant Follicular Lymphoma Prior to High Dose Therapy as In Vivo Purging and to Maintain Remission Following High Dose Therapy
Keywords rituximab, mabthera, follicular, non-hodgkin's, lymphoma, LYM, relapse, resistant

Study Code MMVAR
Study Title
A randomized controlled study of Velcade (Bortezomib) plus Thalidomide plus Dexamethasone compared to Thalidomide plus Dexamethasone for the treatment of myeloma patients progressing or relapsing after autologous transplantation
Keywords velcade, bortezomib, thalidomide, dexamethasone, myeloma, MM, autologous, MMVAR

Study Code MUDRIC-MM
Study Title
Allogeneic Stem Cell Transplantation from Unrelated Donors After Dose Reduced Intensity Conditioning Regimen for Patients with Multiple Myeloma and Relapse After Autologous Stem Cell Transplantation
Keywords myeloma, MM, allogeneic, RIC, unrelated, relapse

Study Code Myfortic - GvHD
Study Title
A Randomized Double Blinded Placebo-Controlled Trial Comparing Cyclosporine plus Steroids with or without Myfortic as Primary Treatment for Extensive Chronic Graft Versus Host Disease
Keywords GvHD, graft versus host disease, extensive, myfortic, allogeneic, myeloablative, MA, non-myeloablative, NMA

Study Code OKT3 - GVHD
Study Title
Treatment of severe GvHD: a prospective cohort study determining factors affecting resistance to standard steroid treatment with a nested randomized study comparing high dose steroids with or without OKT3 in steroid-resistant GvHD
Keywords GVHD, graft versus host disease, severe, acute, OKT3, high dose, allogeneic

Study Code POMA
Study Title
Audit of incidence and management of oral mucositis in adult patients with Multiple Myeloma or Non-Hodgkin’s Lymphoma undergoing autologous PBPC transplantation in Europe
Keywords myeloma, MM, non-hodgkin’s, lymphoma, autologous, POMA

Study Code Random-ICE
Study Title Randomized Trial of Sequential High Dose Chemotherapy versus Standard Chemotherapy for the Treatment of Small-Cell Lung Cancer
Keywords small cell, lung, high dose, ICE

Study Code RATGAA07
Study Title Prospective Phase II study of Rabbit Antithymocyte globulin (ATG, Thymoglobuline®, Genzyme) with ciclosporin for Patients with Acquired Aplastic Anaemia and comparison with matched historical patients treated with horse ATG and ciclosporin
Keywords Thymoglobuline
Rabbit ATG
Ciclosporin
Aplastic Anemia

Study Code RICMAC
Study Title
Dose-reduced versus standard conditioning followed by allogeneic stem cell Transplantation in patients with MDS or sAML
Keywords MDS, myelodysplasia, AML, myeloid, allogeneic, RIC

Study Code SAA-G-CSF
Study Title A Randomized Controlled Study in Newly Diagnosed Severe Aplastic Anaemia Patients Receiving Antithymocyte Globulin (ATG), Cyclosporin A, with or without G-CSF
Keywords severe, aplastic anaemia, AA, SAA, G-CSF, ATG, CsA

Study Code STWP-02
Study Title
Allogeneic Stem Cell Transplant With Minimal or Reduced Conditioning For The Treatment of Patients with Advanced Solid Tumours:
Phase I protocols for breast, ovarian cancer, renal cell carcinoma, soft tissue sarcomas, colorectal carcinoma, melanoma, lung carcinoma and biliary tree adenocarcinoma
Keywords allogeneic, solid tumour, phase I, breast, ovarian,renal cell carcinoma, soft tissue sarccoma, colorectal, melanoma

Study Code VOD-DF
Study Title
Prospective Study of the Incidence and Outcome of Veno-occlusive Disease (VOD) with the Prophylactic Use of Defibrotide (DF, Gentium, Italy) in Pediatric Stem Cell Transplantation
Keywords pediatric, veno occlusive disease, VOD, defibrotide, DF

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