Lymphoma

Last updated: 15.01.2008

Questionnaires & Surveys

EBMT CLWP and LWP survey on the outcome of autologous and allogeneic stem cell transplantation for Richters transformation

The CLL subcommittee of the Chronic Leukemia Working Party is conducting a survey to identify patients with Richter's transformation. Currently these patients are not clearly registered in the EBMT data base. We hope that your participation in collecting data for this small but very interesting patient's group, will help to provide further data concerning a retrospective survey regarding patients transplanted from 1997 to 2006.

To download a pdf version of the survey, click here

Data will be collected through a pre filled MedB form, click here

Additional Information can be found in the study invitation letter, click here

The survey should be completed and sent to the address below or to the following fax number +49 180 500 290 623 or +49 711 4900 8723 before 30th November, 2007

Data Office
Chronic Leukaemia Working Party
Department of Medical Statistics & Bioinformatica
Postzone S-05-P LUMC, PO Box 9600
2300 RC Leiden, The Netherlands
e-mail: clwpebmt@LUMC.NL

Ongoing Studies

Prospective Clinical Trials of the LWP

• Randomised Study of Rituximab (Mabthera) in Patients with Relapsed Follicular Lymphoma Prior to High Dose Therapy as In Vivo Purging and to Maintain Remission Following High Dose Therapy
  (R. Pettengell, AH. Golstone )
  Most recent presentation at Hamburg March 06

Click on the following links to download:
Complete Protocol 16.01.2002
Patient Information 05.12.1999
Letter for General Practitioners
Eligibility Criteria and Randomisation Forms 01.2002

• Allogeneic Peripheral Blood Progenitor Cell Transplantation After Reduced Conditioning for Primary Refractory or Relapsed Hodgkin's Disease
  ( A. Sureda, N. Schmitz )
  Most recent presentation at Hamburg March 06
  Complete Protocol 26.06.06
  
  

• A Randomised Trial of BEAM plus PBSCT versus Single Agent High-dose Therapy Followed by BEAM plus PBSCT in Patients with Chemosensitive Relapsed Hodgkin’s Disease.
  (A. Jösting, A. Engert)
  Most recent presentation at Hamburg March 06

Trial Co-ordinator for LWP Prospective Trials: Kim Champion

New Proposals

• EBMT study for first line allo transplants of T-NHL
  (N.Schmitz)
  Slide presentation at Hamburg March 06
• Allogeneic Stem Cell Transplantation for HIV positive patients with lymphoma
  (I.Gabriel)
  Slide presentation at Hamburg November 07
  

Retrospective Analysis of the LWP

Hodgkin's lymphoma

Allogeneic hematopoietic stem cell transplantation in children with Hodgkin's lymphoma
A. Claviez			Manuscript in preparation
Most recent presentation Hamburg 06
Outcome of non-myeloablative conditioning for allogeneic stem cell transplantation in Hodgkin's lymphom
S. Robinson			Manuscript Submitted
Synopsis
Most recent presentation Hamburg 06
Late toxicity effects after autologous stem cell transplantation in Hodgkin's lymphoma. A joint study with the Late Effects WP
A. Josting, M. Sieniawski			Data Acquisition
Synopsis
Autologous transplantation followed by reduced-intensity allogeneic stem cell transplantation in patients with Hodgkin's lymphoma
I. Alvarez A.Sureda			Data Acquisition
Synopsis

Non-Hodgkin's lymphoma

Allogeneic transplantation in children with non Hodgkin's lymphoma.
A. Claviez		Manuscript in preparation
Matched unrelated donor stem cell transplantation for patients with follicular lymphoma: A retrospective analysis of 125 patients registered through the EBMT
I. Avivi		Submitted
Synopsis
Allogeneic stem cell transplantation for angioimmunoblastic lymphoma
C. Kyriakou		Manuscript in preparation
Synopsis
Reduced intensity conditioning allogeneic stem cell transplantation in mantle cell lymphoma: An update from the LWP of the EBMT
S. Robinson		Data acquisition / Request to centres for histological review
Synopsis
Matched unrelated donor stem cell transplantation for patients with mantle cell lymphoma
I. Avivi		Data acquisition / Request to centres for histological review
Synopsis
Matched unrelated donor stem cell transplantation for patients with B cell difuse non Hodgkin's lymphoma
I. Avivi		Final Data Analysis
Autologous and allogeneic stem cell transplantation for lymphoplasmacytic lymphoma
C. Kyriakou		Manuscript in preparation

Reduced intensity allogeneic stem cell transplantation versus autologous stem cell transplantation in patients with follicular lymphoma.
S. Robinson		Data acquisition
Most recent presentation Hamburg 06
Autologous transplantation for lymphoma in HIV+ patients: A matched-paired analysis with HIV negative patients
J.L. Diez		Manuscript in preparation
Synopsis
Most recent presentation Hamburg 06
Allogeneic and autologous stem cell transplantation for peripheral T-cell lymphoma.
M. Nickelsen		Data acquisition
Synopsis
Transplantation outcome in testicular lymphoma
Argiris Symeonidis		Final Data Analysis/ Manuscript in preparation
Synopsis
Most recent presentation Hamburg 06

Reduced intensity allogeneic haematopoietic stem cell transplantation for follicular lymphoma using different approaches for GVHD prophylaxis.
J.Delgado		Data Aquisition
A retrospective comparison of reduced intensity allogeneic stem cell transplantation from a matched sibling versus a matched unrelated donor in follicular lymphoma.
I.Avivi		Data Aquisition
Autologous Stem Cell Transplantation (ASCT) for Elderly Patients (> 60 years) with non-Hodgkin’s Lymphoma (NHL): an Analysis Based on EBMT Registry
E.Jantunen		Manuscript submitted to JCO
High dose therapy and autologous stem cell transplantation for relapsed aggressive lymphoma patients: A study taking the patients as its own control.
C. Gisselbrecht / N. Mounier		Data Aquisition
A study of the relative survival analysis of diffuse large B-cell lymphoma patients after front-line autologous stem cell transplantation.
C.Gisselbrecht / N. Mounier		Data Aquisition
Autologous and allogeneic stem cell transplantation for Richter's transformation: a retrospective analysis from the Lymphoma Working Party and Chronic Leukaemia Working Party of the EBMT.
K. Cwynarski
ASCT in HIV positive Patients with Lymphomas. A Comparison with a Matched HIV negative Population
P.Balsolobre		Data Aquisition

Joint studies EBMT/IBMTR

HLA identical sibling allogeneic stem cell transplantation versus HLA matched unrelated donor allogeneic stem cell transplantation in patients with follicular lymphoma.
A. Sureda & H. Schouten	Data Aquisition
Proposal Slides

For more information on the Retrospective Studies you may contact the study co-ordinator and statistician Carmen Canals

New Proposals