Publications

To see 'ALWP Updates' written for the EBMT News click here

V Rocha, M Labopin, E Gluckman. Umbilical cord blood for transplantation in adults. NEJM. 352:936-7, 2005

Aoudjhane M, Labopin M, Gorin NC, Shimoni A, Ruutu T, Kolb HJ, Frassoni F, Boiron JM, Yin JL, Finke J, Shouten H, Blaise D, Falda M, Fauser AA, Esteve J, Polge E, Slavin S, Niederwieser D, Nagler A, Rocha V; Acute Leukemia Working Party (ALWP) of the European group for Blood and Marrow Transplantation (EBMT). Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic haematopoietic stem cell transplantation for patients older than 50 years of age with acute myeloblastic leukaemia: a retrospective survey from the Acute Leukemia Working Party (ALWP) of the European group for Blood and Marrow Transplantation (EBMT). Leukemia. 2005 Dec;19(12):2304-12.

Garderet L, Labopin M, Gorin NC, Polge E, Baruchel A, Meloni G, Ortega J, Vossen J, Bunjes D, Leverger G, Blaise D, Ferrant A, Brune M, Dore E, Gadner H, Zintl F, Yaniv I, Dini G, Frassoni F. Hematopoietic stem cell transplantation for de novo acute megakaryocytic leukemia in first complete remission: a retrospective study of the European Group for Blood and Marrow Transplantation (EBMT). Blood. 2005 Jan 1;105(1):405-9.

Ruutu T, Corradini P, Gratwohl A, Holler E, Apperley J, Dini G, Rocha V, Schmitz N, Socie G, Niederwieser D. Use of intratecathecal prophylaxis in allogeneic haematopoietic stem cell transplantation for malignant blood diseases: a survey of the European Group for Blood and Marrow Transplantation (EBMT). Bone Marrow Transplant. 2005 ;35(2):121-4

Vanderson Rocha, MD, PhD; Myriam Labopin, MS,MD; Guillermo Sanz, MD; William Arcese MD, Rainer Schwerdtfeg, MD, Alberto Bosi MD, Niels Jacobsen MD, Tapani Ruutu MD, Marcos de Lima MD,Jurgen Finke MD, Francesco Frassoni MD, Eliane Gluckman, MD and other members of the Acute Leukemia Working Party of EBMT and Eurocord-Netcord registry. Transplants of umbilical-cord blood or bone marrow from unrelated donors in adults with acute leukemia. New England Journal of Medicine. 2004; 351:2276-85

Bhawna Sirohi, Ray Powles, Claudius Rudin, Samar Kulkarni, Francesco Frassoni, Andrea Baciagalupo, Seema Singhal, Myriam Labopin, Mauricette Michallet, Didier Blaise, Josy Reiffers, Giovanna Meloni, Bernard Rio, Jennifer Treleaven, Clive Horton, Jayesh Mehta. Reassessing autotransplantation for acute myeloid leukaemia in first remission – a matched pair analysis of autologous marrow versus peripheral blood stem cells. Bone Marrow Transplant. 2004; 33(12):1209-14

Fouillard L, Labopin M, Meloni G, Polge E, Gorin NC, Frassoni F. Comparison of BAVC to BuCy regimens in autologous stem cell transplantation for adult patients with acute myeloid leukemia. Haematologica. 2004; 89(1):107-8

Olle Ringdén, Myriam Labopin, Norbert-Claude Gorin, Katarina Le Blanc, Vanderson Rocha, Eliane Gluckman, Jules Reiffers, William Arcese, Jaak M. Vossen, Jean-Pierre Jouet, Catherine Cordonnier and Francesco Frassoni, for the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT). Treatment with granulocyte colony-stimulating factor after allogeneic bone marrow transplantation for acute leukemia increases the risk of graft-versus-host disease and death. J Clin Oncol. 2004 Feb 1;22(3):416-23

Vanderson Rocha, MD, PhD; Myriam Labopin, MS,MD; Guillermo Sanz, MD; William Arcese MD, Rainer Schwerdtfeg, MD, Alberto Bosi MD, Niels Jacobsen MD, Tapani Ruutu MD, Marcos de Lima MD,Jurgen Finke MD, Francesco Frassoni MD, Eliane Gluckman, MD and other members of the Acute Leukemia Working Party of EBMT and Eurocord-Netcord registry. Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia. New England Journal of Medicine. 2004, Nov; 351(22):2265-75

Fouillard L, Labopin M, Meloni G, Polge E, Gorin NC, Frassoni F. Factors influencing outcome and incidence of long-term complications in children who underwent autologous stem cell transplantation for acute myeloid leukemia in first complete remission. Blood 2003 Feb; 101(4):1611-9

Garderet L, Labopin M, Gorin NC, Polge E, Fouillard L, Ehninger GE, Ringden O, Finke J, Tura S, Frassoni F. Patients with acute lymphoblastic leukaemia allografted with a matched unrelated donor may have a lower survival with a peripheral blood stem cell graft compared to bone marrow. Bone Marrow Transplant 2003 Jan;31(1):23-9

Locatelli F, Labopin M, Ortega J, Meloni G, Dini G, Messina C, Yaniv I, Fagioli F, Castel V, Shaw PJ, Ferrant A, Pession A, Socie G, Frassoni F. European Blood and Marrow Transplantation Acute Leukemia Working Party. Factors influencing outcome and incidence of long-term complications in children who underwent autologous stem cell transplantation for acute myeloid leukemia in first complete remission. Blood 2003 Feb 15;101(4):1611-9

Gorin NC;Labopin M;Rocha V;Arcese W;Beksac M;Gluckman E;Ringden O;Ruutu T;Reiffers J;Bandini G;Falda M;Zikos P;Willemze R;Frassoni F; Marrow versus peripheral blood for geno-identical allogeneic stem cell transplantation in acute myelocytic leukemia: influence of dose and stem cell source shows better outcome with rich marrow. Blood. 2003

Gorin NC, Labopin M, Polge E, Cordonnier C, Jouet JP, Michallet M, Blaise D, Reiffers J, Rio B, Milpied N, Frassoni F; Acute Leukaemia Working Party of the European Cooperative Group for Blood and Marrow Transplantation (EBMT). Risk assessment in adult acute lymphoblastic leukaemia before early haemopoietic stem cell transplantation with a geno-identical donor: an easy clinical prognostic score to identify patients who benefit most from allogeneic haemopoietic stem cell transplantation. Leukemia. 2003 Aug; 17(8):1596-9

Van Kempen-Harteveld ML, Belkacemi Y, Kal HB, Labopin M, Frassoni F. Dose-effect relationship for cataract induction after single-dose total body irradiation and bone marrow transplantation for acute leukemia. Int J Radiat Oncol Biol Phys 2002 Apr 1;52(5):1367-74

Rocha V, Labopin M, Gluckman E, Powles R, Arcese W, Bacigalupo A, Reiffers J, Iriondo A, Ringden O, Ruutu T, Frassoni F. Acute Leukemia Working Party of the European Blood and Marrow Transplant Registry. Relevance of bone marrow cell dose on allogeneic transplantation outcomes for patients with acute myeloid leukemia in first complete remission: results of a European survey. J Clin Oncol 2002 Nov 1;20(21):4324-30

Fouillard L, Labopin M, Gratwohl A, Powles R, Bacigalupo A, Bego G, Chesnel V, Gorin NC. European Group for Blood and Marrow Transplantation (EBMT). Outcome of 5651 hematopoietic stem cell transplants for hematological malignancies carried out in Europe in 1993: a reliability study of the registry. Bone Marrow Transplant 2002 Nov;30(10):637-43

Fouillard L, Labopin M, Gorin NC, Polge E, Prentice HG, Meloni G, Reiffers J, Pigneux A, Willemze R, Schattenberg A, Sica S, Lagrange M, Fenneteau O, Perot C, Frassoni F. Acute Leukemia Working Party of the EBMT. Hematopoietic stem cell transplantation for de novo erythroleukemia: a study of the European Group for Blood and Marrow Transplantation (EBMT). Blood 2002 Nov 1;100(9):3135-40

Ringden O, Labopin M, Bacigalupo A, Arcese W, Schaefer UW, Willemze R, Koc H, Bunjes D, Gluckman E, Rocha V, Schattenberg A, Frassoni F. Transplantation of peripheral blood stem cells as compared with bone marrow from HLA-identical siblings in adult patients with acute myeloid leukemia and acute lymphoblastic leukemia. J Clin Oncol 2002 Dec 15;20(24):4655-64

A Bosi, D Laszlo, M Labopin, E Gluckman, PE Alessandrino, F Locatelli, J Sierra and F Frassoni Second Allogeneic Bone Marrow Transplantation in Acute Leukemia: Results of a Survey by the European Cooperative Group for Blood and Marrow transplantation (EBMT) of 170 cases. Journal of Clinical Oncology, 2001.

V Rocha, M Labopin, E Gluckman, T Ruutu, W Arcese, J Reiffers, A Iriondo, O Ringdén and F Frassoni on behalf of the Acute Leukemia Working Party (ALWP) of the European Blood and Marrow Transplant (EBMT) registry. The results of allogeneic transplant for acute myeloid leukaemia can be consistently improved by increasing the bone marrow cell dose. A European survey. Submitted

Frassoni F, Labopin M, Powles R, Mary JY, Arcese W, Bacigalupo A, Bunjes D, Gluckman E, Ruutu T, Schaefer UW, Sierra J, Vernant JP, Willemze R, de Witte T, Gorin NC. Effect of centre on outcome of bone-marrow transplantation for acute myeloid leukaemia. Acute Leukaemia Working Party of the European Group for Blood and Marrow Transplantation. Lancet. 2000 Apr 2;355(9213):1393-8

J Reiffers, M Labopin, M Sanz, M Korbling, D Blaise, J De La Rubia, NC Gorin. Autologous blood cell versus marrow transplantation for acute myeloid leukemia in complete remission: an EBMT retrospective study. Bone Marrow Transplant. 2000 Jun;25(11):1115-9.

O Ringden, M Labopin, NC Gorin, F Mandelli, D Blaise, J Reiffers, B Simonsson, F Frassoni. The dismal outcome in patients with acute leukaemia who relapse after an autograft is improved if a second autograft or a matched allograft is performed. Bone Marrow Transplant. 2000 May;25(10):1053-8.

J.Y Cahn, M Labopin, J Sierra, D Blaise, J Reiffers, A Ferrant, L Bergmann, G Visani, J Cornelissen, T De Witte, A Bosi F Frassoni and NC Gorin. No impact of high-dose cytarabine on the outcome of patients transplanted for acute myeloblastic leukemia in first remission. British Journal of Haematology 2000; 110: 308-314.

NC Gorin, M Labopin, P Pichard, J Sierra, D Fiere, B Rio, G Meloni, A Sanz, A Iriondo, F Frassoni, for the Acute Leukemia Working Party of The European Group for Blood and Marrow Transplantation. Feasibility and recent improvement of autologous stem cell transplantation for acute myelocytic leukaemia in patients over 60 years of age: importance of the source of stem cells. British Journal of Haematology 2000; 110: 1-8.

O Ringden, M Labopin, NC Gorin, N Schmitz, UW Schaefer, HG Prentice, L Bergmann, JP Jouet, F Mandelli, D Blaise, L Fouillard, F Frassoni. Is there a graft-versus-leukemia effect in the absence of graft-versus-host disease in patients undergoing bone marrow transplantation for acute leukaemia? British Journal of Haematology 2000; 111: 1130-1137.

O. Ringden, M Labopin, F Frassoni, GF Sanz, F Demeocq, HG Prentice, JY Cahn, T Barbui, G Meloni, UW Schaefer, J Reiffers, NC Gorin. Allogeneic bone marrow transplantation or second autograft in patients with acute leukemia who had relapse after an autograft. Bone Marrow transplantation 1999, 24: 389-396.

Belkacemi Y, Labopin M, Vernant JP, Prentice H, Tichelli A, De Witte T, Boogaerts M, Ernst P, Della Volpe A, Goldstone A, Jouet JP, Verdonck L, Rio B, Locasciulli A, Ozsahin M, Gorin NC. Cataracts following bone marrow transplantation conditioned with total body irradiation in patients with acute leukemia in first remission. International Journal of Radiotherapy and Biological Physics, 1998, 41 (3): 659-68.

O. Ringden, M. Labopin, E. Gluckman, J. Reiffers, J.P. Vernant, J.P. Jouet, Jl. Harrousseau, D. Fiere, A. Bacigalupo, F. Frassoni and N.C. Gorin For the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation: Strong antileukemic effect of chronic graft versus host disease in allogeneic marrow transplant recipients having acute leukemia treated with methotrexate and cyclosporine. Transplantation Proceedings 1997, 29: 733-34

Ringden O, Labopin M, Fouillard L, Gluckman E, Jacobsen N, Vernant JP, Boogaerts M, Witz F, Harousseau JL, Gorin NC . A comparison of outcome aftre bone marrow transplantation using unrelated or autologous bone marrow transplantation in acute leukemia. Experimental Hematology, proceedings of the 24th Meeting of the International Society for Experimental Hematology in Düsseldorf. 1997

O. Ringden, M. Labopin, E. Gluckman, Jm. Hows, Ba. Bradley, HJ. Kolb, L Fouillard, N. Jacobsen, JP Vernant, F. Witz, JL. Harousseau, NC Gorin for the Acute Leukemia Working-Party of the European Cooperative Group for Blood and Marrow Transplantation (EBMT) and the International Marrow Unrelated Search and Transplant (IMUST) Study: Donor search or autografting in patients with acute leukemia who lack an HLA-indentical sibling? A matched-pair analysis. Bone Marrow Transplantation, 1997, 19: 963-68

JY. Cahn, M. Labopin, A. Schattenberg, J. Reiffers, R. Willemze, R. Zittoun, A. Bacigalupo, G. Prentice, E. Gluckman, P. Herve, A. Gratwohl and NC. Gorin: Allogeneic bone marrow transplantation for acute leukemia in patients over the age of 40 years. Leukemia 1997, 11: 416-19

A. Ferrant, M. Labopin, F. Frassoni, HG. Prentice, JY Cahn, D. Blaise, J. Reiffers, G. Visani, MA. Sanz, MA. Boogaerts, B. Löwenberg and NC. Gorin on behalf of the Acute Leukemia Working Party of the European Cooperative Group for Blood and Marrow Transplantation (EBMT): Karyotype in acute myeloblastic leukemia: prognostic significance for bone marrow transplantation in first remission: a European group for blood and marrow transplantation study. Blood, 1997, 90: 2931-38

T. De Witte, A. Van Biezen, J. Hermans, M. Labopin, V. Runde, R. Or, G. Meloni, SB. Mauri, A. Carella, J. Apperley, A. Gratwohl and J.Ph Laporte, for the Chronic and Acute Leukemia Working-Parties of the European Group for Blood and Marrow Transplantation. Autologous bone marrow transplantation for patients with myelodysplastic syndrome (MDS) or acute leukemia following MDS. Blood, 1997, 90: 3853-57.

F. Frassoni, M. Labopin, E. Gluckman, H.G. Prentice, J.P. Vernant, F. Zwaan, A. Granena, G. Gahrton, T. De Witte, A. Gratwohl, J. Reiffers and N.C. Gorin: Results of allogeneic bone marrow transplantation for acute leukemia have improved in Europe with time: a report of the acute leukemia working party of the european group for blood and marrow transplantation (EBMT), Bone Marrow Transplantation, 1996, 17, 13-18.

O. Ringden, M. Labopin, S. Tura, G. Meloni, A. Iriondo, R. Zittoun, J. Sierra and N.C. Gorin: A comparison of busulphan vs. Total body irradiation combined with cyclophosphamide as conditioning for autograft or allograft bone marrow transplantation in patients with acute leukaemia. Brit. J. of. Hemat, 1996, 93,637-645

N.C. Gorin, M. Labopin, L. Fouillard, G. Meloni, F. Frassoni, A. Iriondo, S. Brunet, Ah. Goldstone, Jl. Harousseau, J. Reiffers, H. Esperou-Bourdeau and E. Gluckman: Retrospective evaluation of autologous bone marrow transplantation versus allogeneic bone marrow transplantation from an HLA identical related donor in acute myelocytic leukemia. A study of the european cooperative group for blood and marrow transplantation (EBMT). Bone Marrow Transplantation, 1996, 111-117.

O. Ringden, M. Labopin, E. Gluckman, J. Reiffers, J.P. Vernant, J.P. Jouet, Jl. Harrousseau, D. Fiere, A. Bacigalupo, F. Frassoni and N.C. Gorin. For the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation: Graft-versus-leukemia effect in allogeneic marrow transplant recipients with acute leukemia in not abrogated using cyclosporin combined with methotrexate. Bone Marrow Transplantation, 1996, 18: 921-29

O. Ringden, Jr Mentz, M. Labopin, J. Apperley, Nc. Gorin and A. Gratwhol: for the acute and chronic leukemia working-parties of the european group for blood and marrow transplantation (EBMT): the highest leukemia-free-survival after allogeneic bone marrow transplantation is seen in patients with grade 1 acute graft versus host disease. Leukemia & Lymphoma, 1996, 24: 71-79

Schmitz N, Bacigalupo A, Labopin M, Majolino I, Cook G, Laporte JP, Rozman C, Lambertenghi-Deliliers G, Lange A, Brinch L, Gratwohl A. Transplantation of peripheral blood progenitor cells from HLA-identical sibling donors. British Journal of Haematology, 1996, 95, 715-723.

JY Cahn, M. Labopin and N C. Gorin: Autologous bone marrow transplantation for first remission acute myeloblastic leukemia in elderly patients: a retrospective analysis of the European Bone Marrow Transplant Registry (EBMT). Blood. 1995 Jan 15;85(2):575-9

M. Labopin, N.C. Gorin: Autologous bone marrow transplantation in acute myelocytic leukemia in Europe: the role of marrow purging. Acute Leukemia IV, Prognostic factors, Büchner t al (Eds). Springer-Verlag, Berlin Heidelberg, 1994, 673-680

F. Frassoni, M. Labopin, E. Gluckman, Hg Prentice, G. Gahrton, F. Mandelli, M. Carella, P. Herve, A. Gratwohl, J. Goldman, and N.C. Gorin, on behalf of the Acute Leukemia Working Party of the European Group for Bone Marrow Transplantation (EBMT): Are patients with acute leukaemia, alive and well 2 years post-bone marrow transplantaiton cured ? A european survey. Leukemia 1994, 8, 6, 924-28

F. Mandelli, M. Labopin, A. Granena, A. Iriondo, G. Prentice, A. Bacigalupo, J. Sierra, G. Meloni, F. Frassoni, J. Goldman, A. Gratwohl, and N.C. Gorin: On behalf of the working-party on acute leukemia of the European Cooperative Group for bone Marrow Transplantation (EBMT). European survey of the role of bone marrow transplantation in acute promyelocytic leukemia (M3). Bone Marrow Transpl 1994, 14, 293-98.

T. De Witte, A. Van Biezen, J. Hermans, M. Labopin, A. Gratwohl, N.C. Gorin: Autologous bone marrow transplantation for patients with myelodysplastic syndrom (MDS) or acute myeloid leukaemia following MDS (sAML). International J of Pediatric Hematology/Oncology, Proceedings of the symposium on bone marrow failure, Moscow, September 8-12, 1994.

P. Herve, M. Labopin, E. Plouvier, P. Palut, P. Tiberghien, N.C. Gorin: Autologous bone marrow transplantation for childhood acute myeloid leukemia: a European survey. Bone Marrow Transpl. 1991;8 Suppl 1:76-9

W.C. Aird, M. Labopin, N.C. Gorin, J.H Antin: Long-term cryopreservation of human stem cells. Bone Marrow Transpl. 1992, 9, 487-490

M. Labopin, N.C. Gorin: Autologous bone marrow transplantation for acute leukemia in Europe. Proceedings of the Genoa Meeting. Leukemia, 1992, 6 (suppl.4), 95-99

N.C. Gorin, M. Labopin, G. Meloni, M. Korbling, A. Carella, P. Herve, A. Brunett, V. Rizzoli, Ep Alessandrino, B.Bjorkstrand, A. Ferrant, B. Lowenberg, P. Coser, B. Simonsson, W. Helbig, S. Brunet-Mauri, Lf Verdonck, A. Iriondo, E. Polli, P. Colombat, Im Franklin, G. Souillet and R. Willemze: Autologous bone marrow transplantation for acute myeloblastic leukemia in Europe: further evidence of the role of marrow purging by mafosfamide. Leukemia, 1991, 5, 10, 896-904

P. Herve, M. Labopin, E. Plouvier, P. Palut, P. Tiberghien, N.C. Gorin: Autologous bone marrow transplantation for childhood acute lymphoblastic leukemia. A European survey, EBMT working party on ABMT. Bone Marrow transpl. 1991, 8, sup.1, 72-75

EBMT News Updates (click on the pdf symbol)

March 2005