Acute Leukaemia

Studies

The period of inclusion for the REGISTRATION STUDY has been extended until December 2006. 559 patients have been included on November 2005 - update available here

Ongoing Studies
Prospective Studies

Ongoing Studies:

1. A retrospective study on family haploidentical allogeneic stem cell transplantation in Europe (Ciceri) Abstract & Synopsis
2. Family Haploidentical Haematopoeitic Stem Cell Transplantation for paediatric acute leukaemia. A European retrospective study on behalf of the acute leukaemia and paediatric working parties of the EBMT. (J Cornish, T Klingebiel, Giorgio Dini) Abstract & Synopsis
3. Outcomes of unrelated cord blood and Haploidentical stem cell transplantation in adults with acute leukaemia (V Rocha, F Aversa) Abstract
4. Retrospective comparison of Haplo-Identical Haematopoietic Stem Cell versus Cord Blood Transplantation for paediatric acute leukaemia (R Hough, V Rocha, E Gluckman) Abstract & Synopsis
5. Results of transplantation for APL
   (M Sanz, J. De la Rubia)
6. High dose etoposide to intensify standard conditioning regimens fails to ameliorate the post transplant outcome: a pair matched analysis from the EBMTG leukaemia WP. (EP Alessandrino)
7. Autologous bone marrow transplantation in 2nd CR AML: comparison of results obtained reinfusing HSC harvested either in 1st or 2nd CR. An ALWP EBMT study. (G Meloni)
8. Double autografts in acute leukemia. (J Sierra)
9. BAVC VS BUCY in autograft for AML in adults in CR1 (L Fouillard)
10. Comparison of peripheral blood versus bone marrow allogeneic transplantation for acute leukemia on hla identical sibling donor.
    (Ringdén)
11. The choice between bone marrow versus peripheral blood for patients undergoing allogeneic transplant for AML 1CR should be based on the marrow cell dose. A survey of EBMT since 1994. (F. Frassoni)
12. Age effect on outcome of patients with aml after hla identical sibling transplantation. (J. Sierra)
13. Risk factors for chronic GvHD after Allogeneic Peripheral Blood Stem Cell Transplants (allo-PBSCT) in patients with Acute Leukemia (AL)
    (V. Rocha)
14. Role of GVHD-GVL in preventing relapse in high risk AML.
    (W Arcese and C Guglielmi)
15. Influence of HLA alleles on outcome after HLA identical transplants.
    (V. Rocha)
16. MUD in adults AL (V. Rocha)
17. Q Twist and competing risks in AL (R. Porcher, M. labopin)
18. MUD in childhood ALL (F Locatelli)
19. Evaluation of the influence of total body irradiation parameters, such as dose rate, on outcome for patients receiving reduced intensity regimen transplants. (Y. Belkacemi)
20. Survey of adults patients receiving HLA identical SCT for ALL in CR1
    (NC.Gorin)
21. Results of stem cells transplantation in patient with AML 7. (L Garderet)
22. Role of phenotype on outcome in children with ALL. (F Locatelli)
23. Outcome of Children with 2CR ALL for whom a search for a MUD is activated (G Dini)
24. Comparison of MUD, related haploidentical, unrelated cord blood transplants in adults with acute leukemia (synopsis, methodology, feasibility…) (V Rocha, M Labopin)

Prospective studies:

1. Prospective registration study: Efficiency of the strategy of donor search for stem cell transplant for patients with acute leukemia
   (Y Reisner, E Gluckman , F. Frassoni)
   
   
2. STI-571 after transplant in Philadelphia positive ALL (O. Ottmann , J.J. Cornelissen , D. Holzer)
   
   
3. REGISTRATION STUDY: (participation deadline extended until December 2006) to evaluate the contribution of different strategies of treatment (HLA-identical siblings and other treatments including alternative stem cell transplant) for children and adult patients with Acute Leukaemia. (F Frassoni , V Rocha , M Labopin )
   
   Documentation:
   Adults Registration Study (219kb)
   Children's Registration Study (223kb)
   RS Agreement (31kb)
   RS Letter & Agreement (44kb)
   RS Registration Form (402kb)
   All of the above documents in 1 zip file (392kb)
   
   Registrations Study Update, November 2005