Transplant Activity Survey

Background

In 1990, the EBMT introduced an annual survey to prospectively collect numbers of patients treated with a hematopoetic stem cell transplant according to indication, donor type and stem cell source. Its importance was immediately realised and since then, the survey has become an instrumental tool for assessing the real picture of HSCT in Europe, recognising trends, illustrating the current status and providing essential data for counselling and planning. This survey is relevant to health care agencies, industries as well as patients. In addition, it serves as a quality control instrument for comparison with national agencies or for the EBMT auditing process.

All transplant teams are invited to join the survey: for EBMT members it is a mandatory process, for non-members it is voluntary.

Participate in the 2007 Activity Survey

Participate in the 2007 Activity Survey Data reported to the EBMT Med AB database -Promise- is not automatically included in the Activity Survey. Even if you report your transplant data to the EBMT, by paper Med A form, electronically with the ProMISe system or via a National Registry, please report to this survey too.

• EBMT Calender Year Survey 2007 download in either excel pdf
• Guidelines for Activity Survey 2007
  
• Letter requesting CIC participation in Activity Survey 2007

Instructions:

1. Click on the link 'EBMT Calender Year Survey 2007'
2. Save the file to your Desktop or another easy to remember location.
3. Name the file "CIC (your number)". If you do not have a CIC number, call the file after your institution.
4. Complete the data fields.
5. Email the form to the survey coordinator at baldomeroh@uhbs.ch.

The 2007 calendar year survey may be accessed by clicking on the link above. New in this years survey is the collection of data on the numbers of patients given mesenchymal stromal (stem) cells (MSC) and the numbers of patients given hematopoietic stem cells (HSC) for non hematopoietic use. We realise that such treatments may be undertaken by a different department within your institution and that you may not have access to this data. In such cases please mark the fields with an asterix (*).

We recommend that you read the guidelines carefully before filling out the survey.

Please report transplants that have been performed in 2007 only:

• All first allogeneic transplants and first autologous transplants should be reported according to indication, donor type and stem cell source in the main Table 1.
• Other transplants, which are not the patient's first allograft or first autograft, can be reported in Table 2 (if allogeneic) or Table 3 (if autologous).
• First cord blood transplants can be reported in Table 1 by disease category. You can also report any 'retransplants or additional transplants' performed using cord blood transplants in as a total number in Table 2. As a control please report the total number of cord blood transplants in Table 4.
• Reduced Intensity Conditioning transplants (RIC) and patients receiving Donor Lymphocyte Infusions (DLI) can be entered in Table 4.
• Patients receiving Mesenchymal stem cells (MSC) can be reported in Table 4 as a total number.
• Patients receiving Hematopoietic Stem Cells (HSC) for non hematopoietic use (i.e. for cardiovascular or neurological use or for tissue repair) can be reported in Table 4 as a total.
• Table 5 provides us with the total number of all transplants performed in 2007 by adding together the totals of Table 1, 2 and 3.
• In addition we would like to know how many of the allogeneic transplants are part of a planned auto/mini allograft protocol. To report these numbers use the column on the left side of Table 1. Please report the total number of allografts by indication which have been part of a planned 'auto/mini allo' transplant program. These transplants should also be reported in Table 1 as with other first transplants. Do not include these numbers in the totals of Table 1.
  

Summary Slides

Data from the most recent survey year are available only to EBMT members using their username and password. Please contact the EBMT secretariat with any password queries or difficulties.

Transplant Activity Survey 2006

Overview of HSCT in Europe 2006


Transplant Activity Survey 2005

Overview of HSCT in Europe 2005


Transplant Activity Survey 2004

Overview of HSCT in Europe 2004

Please note that this data has not yet been published and should be treated as confidential. It is for internal use only and may not be used for publication without obtaining prior consent from Prof. Alois Gratwohl, Head of the survey.

Please contact Helen Baldomero should you have any questions regarding the Activity survey. Tel: +41 61 2653203 baldomeroh@uhbs.ch.

Previous years

• Activity survey archive (open access)

Publications

Activity Survey 2006: Focus on the use of cord blood products
A.Gratwohl, H.Baldomero,.K.Frauendorfer, V.Rocha, J.Apperley and D.Niederwieser,for the Joint Accreditation Committee of the International Society for Cellular Therapy ISCT and the European Group for Blood and Marrow Transplantation EBMT(JACIE)

Predictability of Hematopoietic Stem Cell Transplantation Rates
Alois Gratwohl, Helen Baldomero, Alvin Schwendener, Michael Gratwohl, Jane Apperley,Dietger Niederwieser, Karl Frauendorfer for the Joint Accreditation Committee of theInternational Society for Cellular Therapy (ISCT), the European Group for Blood and MarrowTransplantation (EBMT) (JACIE) and for the European Leukemia Net

Haematopoietic stem-cell tranplants for Chronic Myeloid Leukemia in Europe. Impact of
cost consideration. A.Gratwohl, H. Baldomero, A. Schwendener, M.Gratwohl, A. Urbano.Ipizua,and K. Frauendorfer for the Joint Accreditation Committee of the International Society for Cellular Therapy ISCT and the European Group for Blood and Marrow Transplantation EBMT (JACIE). Division of Hematology, Department of Medicine, University Hospital Basel, Basel, Switzerland. Institute for Operations Research and Computational Finance, University of St. Gallen, St. Gallen, Switzerland and JACIE Office, Hospital Clinic, Barcelona, Spain.

Results of the EBMT Acitivity Survey 2005 on haematopoietic stem cell transplantation: a focus on increasing use of unrelated donors. A Gratwohl, H.Baldomero, K.Frauendorfer, A.Urbano-Ispizua, and D.Niederwieser, for the Joint Accreditation Committee of the International Society for Cellular Therapy ISCT and the European Group for Blood and Marrow Transplantation EBMT (JACIE).

Change in stem cell source for hematopoietic stem cell transplantation (HSCT) in Europe: a report of the EBMT activity survey 2003. A Gratwohl, H Baldomero, O Schmid, B Horisberger, M Bargetzi and A Urbano-Ispizua for the Joint Accreditation Committee of the International Society for Cellular Therapy ISCT and the European Group for Blood and Marrow Transplantation EBMT (JACIE). Bone Marrow Transplantation 08/08/05 doi:10.1038/sj.bmt.1705104. 437 kb

Evolution of Hematopoietic Stem Cell Transplantation in Eastern andWestern Europe from 1990 to 2003. A Report from the EBMT Activity Survey. Alois Gratwohl, Helen Baldomero, Boris Labar, Jane Apperley, Alvaro Urbano-Ispizua for the Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT). CMJ (2004) 45(6):689-694 150 kb

Haematopoietic stem cell transplantation (HSCT) in Europe 2002. Changes in indication and impact of team density. A report of the EBMT activity survey. A Gratwohl, O Schmid, H Baldomero, B Horisberger and A Urbano-Ispizua, for the Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT). Bone Marrow Transplantation (2004) 34, 855–875 418 kb

EBMT EHA Transplantation Overview of transplant activity in Europe. Alois Gratwohl for the EBMT JACIE Accreditation Office. The Hematology Journal (2004), Volume 5, Supplement 3, Pages S29-S33

A. Gratwohl, H. Baldomero, T. Demirer, G. Rosti, G. Dini, R. Ladenstein & A. Urbano-Ispizua. On behalf of the Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT) in cooperation with the Working Party on Solid Tumours (STWP) and the Working Party on Pediatric Diseases (PDWP) Hematopoetic stem cell transplantation for solid tumors in Europe. Annals of Oncology 15: 653-660, 2004 1.13mb | Appendix 65kb

A Gratwohl, H Baldomero, J Passweg, F Frassoni, D Niederwieser, N Schmitz and A Urbano-Ispizua for the Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT) in cooperation with the Working Parties Acute (ALWP) and Chronic Leukemias (CLWP) and the Lymphoma Working Party. Hematopoietic stem cell transplantation for hematological malignancies in Europe. Leukemia (2003) 17, 941-959

Gratwohl A. The role of the EBMT activity survey in the management of hematopoietic stem cell transplantation. European Group for Blood Marrow Transplantation. Int J Hematol. 2002 Aug;76 Suppl 1:386-92.

A Gratwohl, H Baldomero, J Passweg and A Urbano-Ispizua for the Accreditation Committee of the European Group for Blood and Marrow Transplantation (EBMT). Special report: Increasing use of reduced intensity conditioning transplants: report of the 2001 EBMT activity survey. Bone Marrow Transplantation (2002)30, 813-831

Gratwohl A, Baldomero H, Horisberger B, Schmid C, Passweg J and Urbano-Ispizua A. Current Trends in Hematopoetic Stem Cell Transplantation in Europe. Blood 100: 2374-2386, 2002-10-24, prepublished online May 31, 2002.

Gratwohl A, Passweg J, Baldomero H, Horisberger B, Urbano-Ispizua A. Economics, health care systems and utilization of haematopoietic stem cell transplants in Europe. Br J Haematol. 2002 May;117(2):451-68. PMID: 11972533

Gratwohl A, Baldomero H, Urbano-Ispizua A. Transplantation in chronic myeloid leukaemia. Lancet. 2002 Feb 23;359(9307):712-3. PMID: 11879900

Gratwohl A, Baldomero H. Stem cell transplant numbers decline; research continues. J Natl Cancer Inst. 2001 Jun 20;93(12):949. PMID: 11416117

Gratwohl A, Baldomero H, Rosti G. High-dose chemotherapy for breast cancer. Bone Marrow Transplant. 2000 Sep;26(6):599. PMID: 11041563

Gratwohl A, Passweg J, Baldomero H, Urbano-Ispizua A for the European Group for Blood and Marrow Transplantation (EBMT). Hematopoietic stem cell transplantation activity in Europe 1999. Bone Marrow Transplant. 2001;27:899-916.

Gratwohl A, Passweg J, Baldomero H, Hermans J. Blood and marrow transplantation activity in Europe 1997. European Group for Blood and Marrow Transplantation (EBMT). Bone Marrow Transplant. 1999;Aug24(3):231-45. PMID: 10456992

Gratwohl A, Baldomero H and Hermans J. Quantitative Assessment of Consensus on Indications for Blood or Marrow Transplantation in Europe 1995. Cancer Research Therapy and Control, 1999, Vol. 10, pp. 123-144

Gratwohl A, Passweg J, Baldomero H, Hermans J and Urbano-Ispizua A for the European Group for Blood and Marrow Transplantation. Hematopoietic stem cell transplantation in Europe 1998. The Hematology Journal. 2000;1:333-350.

Gratwohl A, Passweg J, Baldomero H, Hermans J. Blood and marrow transplantation activity in Europe 1996. European Group for Blood and Marrow Transplantation (EBMT). Bone Marrow Transplant. 1998;Aug22(3):227-40. PMID: 9720735.

Gratwohl A, Hermans J, Baldomero H. Blood and marrow transplantation activity in Europe 1995. European Group for Blood and Marrow Transplantation (EBMT). Bone Marrow Transplant. 1997;Mar;19(5):407-19. PMID: 9052905

Gratwohl A, Hermans J, Baldomero H. Hematopoietic precursor cell transplants in Europe: activity in 1994. Report from the European Group for Blood and Marrow Transplantation (EBMT). Bone Marrow Transplant. 1996; Feb;17(2):137-48. PMID: 8640158

Gratwohl A, Hermans J, Baldomero H, Tichelli A, Goldman JM and Gahrton G for the European Group for Blood and Marrow Transplantation (EBMT). Indications for haematopoietic cell transplants in Europe. British Journal Haematology, 1996;92:35-43.

Gratwohl A, Hermans J. Indications and donor source of hematopoietic stem cell transplants in Europe 1993: report from the European Group for Blood and Marrow Transplantation (EBMT). Clin Transplant. 1995;Oct;9(5):355-63. PMID: 8541627

Gratwohl A. Incidence of bone marrow transplantation in Europe. Report from the European Group for Blood and Marrow Transplantation. Arch Immunol Ther Exp (Warsz). 1995;43(2):77-81. PMID: 8744719

Gratwohl A, Hermans J. Bone marrow transplantation activity in Europe 1992: report from the European Group for Bone Marrow Transplantation (EBMT). Bone Marrow Transplant. 1994;Jan;13(1):5-10. PMID: 8019452

Gratwohl A, Hermans J. EBMT survey on bone marrow transplant activity in Europe: regional differences. Bone Marrow Transplant 1994;Jun;13(6):683-8. PMID: 7920292

A. Gratwohl, J. Hermans, J.M. Goldman and G. Gahrton for the European Group for Bone Marrow Transplantation (EBMT). Bone marrow transplantation in Europe: major geographical differences. Journal of Internal Medicine 1993;233:333-341.

Gratwohl A. Bone marrow transplantation activity in Europe 1990. European Group for Bone Marrow Transplantation (EBMT) Bone Marrow Transplant.1991;Sep;8(3):197-201. PMID: 1958899

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